The Inquest is a "meta-krewe", basically an asura corporation whose members are unable to leave unlike a normal krewe, which only comes together to complete a specific task, separating afterwards. Members of the Inquest work towards goals that defy asura ethics. Through their view of the Eternal Alchemy, they believe that the world is a machine which can be run.
As an example of what the Inquest has done, they have in the past taken members of intelligent races and trapped their spirits inside of golems. These experiments, normally done with elementals of lesser sentience, involved physical death for the subject and enslaved them in the process. The other asura think this is going too far.