Lab Sigma-05 is a point of interest in Calon Islet, on the eastern side of the Sandswept Isles. It can only be accessed via the Transport Facility Sigma-05, a hidden Inquest facility located in the Desert Highlands. The lab was used to study the effects of the Scarab Plague on local animals and the Olmakhan and as a storage for Exterminator Mark Golem pieces; it was destroyed in response to the Commander's intrusion. Volatile Magic can be found in the irradiated remains. This is the entrance through living story for the player.
- Radiation Poison is active while inside the lab, dealing 1000 damage per second to the player.
- There are many volatile magic orbs inside the ruins.