From Guild Wars 2 Wiki
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Spectral Darkness is an effect applied by the Spectral Darkness orbs summoned by Gorseval the Multifarious after he finishes his first transition (below 66% health). One orb will grant a stack of 10 Spectral Darkness, the player must walk into two golden colored orbs to remove the 10 stacks. The golden orbs appear after destroying a Spectral Darkness orb.“
Outgoing damage reduced. Incoming damage increased. Reduced health every second. Cured by collecting energy orbs.
— In-game description
Players affected by this have a large 'angry ghost' icon above their heads.